Login Form

DOSY Print E-mail

The DOSY experiment (Diffusion Ordered SpectroscopY) is the measure of diffusion coefficients by NMR. It has been developped in order to facilitate the complexe mixture analysis without physical separation.
Data acquisition and processing required dedicated NMR devices and softwares (NMRnotebook, DOSY Module) and can be speeded up with RDC.

This experiment will monitor any modification of the solvent or of the solutes, and molecular events such as molecular interactions or associations. It can also be used for the separation of molecules present in a mixture, separation based on their different diffusion properties.

There are many different applications:

  • Trace detection and quantification
    Application note available: Using DOSY for complexe mixture analysis

  • Protein / ligand interaction screening (ligands fixed, even partially, to the target protein will see their diffusion coefficient modified). This technique can be applied successfully on ligand libraries.

  • Molecular-mass and branching analysis of polymers

  • Polluant or additive detection (polymers in liquids)

  • Monomer / dimer equilibirum determination
    In-tube NMR "chromatography"

  • Determination of Critical Micellar Concentration

purchase anydvd us buy access 2007 uk buy vmware workstation 7 coupon buy microsoft works download buy acrobat professional 7.0 cheap windows 7 academic best price microsoft project 2007 professional buying adobe illustrator 10 buy final cut pro 4.1 buy windows 7 starter oem
  • discount omnifocus 2010 buy mindjet australia best buy microsoft office 2010 student rosetta stone cheaper version buy office 2011 for mac best buy price of windows 7 basic used autocad 2008 best price adobe photoshop cs2 best price microsoft office price of autocad map 3d 2011